Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.2
USERS' SCORE
Good
Based on 4 Reviews
8.4
Supplement Facts
Serving Size: 2 Veg Capsules
Serving Per Container: 60
Amount Per Serving
%DV
BioCell Collagen® (Hydrolyzed Chicken Sternal Cartilage Extract) providing
1 g (1,000 mg)
**
Hydrolyzed Type II Collagen
570 mg
**
Chondroitin Sulfate
190 mg
**
Hyaluronic Acid
95 mg
**
Top Medical Research Studies
8
Collagen source shows varying effectiveness
We explored the beneficial effects of collagen hydrolysate derived from salmon skin on atherosclerosis, a key contributor to cardiovascular diseases. The study showed that this collagen extract exhibits promising anti-inflammatory and antioxidant properties.
In tests with mice, it effectively reduced arterial thickening and plaque formation without side effects, comparable to the effects of aspirin. However, the results indicate that while collagen from salmon skin has potential, more research is needed before making definitive claims.
In tests with mice, it effectively reduced arterial thickening and plaque formation without side effects, comparable to the effects of aspirin. However, the results indicate that while collagen from salmon skin has potential, more research is needed before making definitive claims.
Read More
8
Collagen supplements may reduce cardiovascular risks
We explored the impact of collagen peptide supplementation (CPS) on cardiovascular disease markers through a careful review of randomized, placebo-controlled trials. Our analysis of twelve studies found that CPS had promising effects, including a decrease in harmful LDL cholesterol and systolic blood pressure, as well as reductions in fat mass.
However, we're clear that CPS did not show any significant effects on blood sugar levels. While these findings are encouraging, further research on CPS with longer durations is needed to fully understand its potential benefits for cardiovascular health.
However, we're clear that CPS did not show any significant effects on blood sugar levels. While these findings are encouraging, further research on CPS with longer durations is needed to fully understand its potential benefits for cardiovascular health.
Read More
8
We explored the potential of collagen hydrolysates from fish skin to impact cardiovascular health, particularly their antiplatelet activity. Eleven peptides were isolated, and nine displayed a Pro-Gly or Hyp-Gly sequence that effectively inhibited platelet aggregation in lab tests. Among these, OGSA showed the strongest effects without increasing bleeding risks. With molecular docking studies suggesting interactions with specific receptors, these peptides may hold promise as dietary supplements for cardiovascular disease prevention.
Read More
Most Useful Reviews
9
Obvious joint improvement
2 people found this helpful
GREAT FOR JOINTS! Type 2 collagen is particularly beneficial for combating joint and cartilage diseases. The product also contains Chondroitin sulfate and Hyaluronic acid. It's crucial to select either type 2 collagen or types 1 and 3, as they cannot be taken simultaneously. I noticed a significant improvement in my joints' condition within a month of use. My knees have especially benefited from this collagen.
Read More
7.5
Relieved back pain
I truly believe this product is aiding my degenerative disc disease. For the past few months, I've suffered from debilitating pain in my lower back. After discovering my mild degenerative disc disease through x-rays, I wanted to heal from within before starting physical therapy. Given that collagen production declines with age, I chose this supplement for its joint benefits. After a few weeks of consistent use, I already feel better and stronger. It's a great value, unlike many collagen products that only focus on types I & III.
Read More
7.5
Effective preventive agent
This is a fantastic collagen for joints! Specifically type 2, it acts as a preventive agent against rheumatism, arthritis, and various inflammatory diseases.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.2
- All Researches
9
We examined the potential of collagen-derived peptides from salmon to combat heart disease, specifically atherosclerosis, in a study involving ApoE mice.
Our findings showed that the peptide OGEFG (OG-5) effectively reduced platelet aggregation and thrombosis by targeting specific receptors and signaling pathways. Additionally, it demonstrated anti-inflammatory effects and decreased atherosclerotic plaque formation compared to traditional treatments like aspirin.
Overall, collagen hydrolysates appear to be a promising dietary supplement for heart health.
Our findings showed that the peptide OGEFG (OG-5) effectively reduced platelet aggregation and thrombosis by targeting specific receptors and signaling pathways. Additionally, it demonstrated anti-inflammatory effects and decreased atherosclerotic plaque formation compared to traditional treatments like aspirin.
Overall, collagen hydrolysates appear to be a promising dietary supplement for heart health.
Read More
8
Collagen source shows varying effectiveness
We explored the beneficial effects of collagen hydrolysate derived from salmon skin on atherosclerosis, a key contributor to cardiovascular diseases. The study showed that this collagen extract exhibits promising anti-inflammatory and antioxidant properties.
In tests with mice, it effectively reduced arterial thickening and plaque formation without side effects, comparable to the effects of aspirin. However, the results indicate that while collagen from salmon skin has potential, more research is needed before making definitive claims.
In tests with mice, it effectively reduced arterial thickening and plaque formation without side effects, comparable to the effects of aspirin. However, the results indicate that while collagen from salmon skin has potential, more research is needed before making definitive claims.
Read More
8
Collagen supplements may reduce cardiovascular risks
We explored the impact of collagen peptide supplementation (CPS) on cardiovascular disease markers through a careful review of randomized, placebo-controlled trials. Our analysis of twelve studies found that CPS had promising effects, including a decrease in harmful LDL cholesterol and systolic blood pressure, as well as reductions in fat mass.
However, we're clear that CPS did not show any significant effects on blood sugar levels. While these findings are encouraging, further research on CPS with longer durations is needed to fully understand its potential benefits for cardiovascular health.
However, we're clear that CPS did not show any significant effects on blood sugar levels. While these findings are encouraging, further research on CPS with longer durations is needed to fully understand its potential benefits for cardiovascular health.
Read More
8
We explored the potential of collagen hydrolysates from fish skin to impact cardiovascular health, particularly their antiplatelet activity. Eleven peptides were isolated, and nine displayed a Pro-Gly or Hyp-Gly sequence that effectively inhibited platelet aggregation in lab tests. Among these, OGSA showed the strongest effects without increasing bleeding risks. With molecular docking studies suggesting interactions with specific receptors, these peptides may hold promise as dietary supplements for cardiovascular disease prevention.
Read More
8
We investigated how Brazilian propolis (AF-08), rich in flavonoids, influences platelet aggregation and its potential role in preventing cardiovascular diseases (CVDs).
Our findings revealed that AF-08 effectively inhibited collagen-induced platelet aggregation without impacting blood coagulation processes.
This suggests that AF-08 may lower the risk of CVDs by preventing harmful platelet clumping while leaving normal blood clotting untouched. Notably, the flavonoids apigenin and chrysin showed significant effects, while kaempferol was less potent.
Our findings revealed that AF-08 effectively inhibited collagen-induced platelet aggregation without impacting blood coagulation processes.
This suggests that AF-08 may lower the risk of CVDs by preventing harmful platelet clumping while leaving normal blood clotting untouched. Notably, the flavonoids apigenin and chrysin showed significant effects, while kaempferol was less potent.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Obvious joint improvement
2 people found this helpful
GREAT FOR JOINTS! Type 2 collagen is particularly beneficial for combating joint and cartilage diseases. The product also contains Chondroitin sulfate and Hyaluronic acid. It's crucial to select either type 2 collagen or types 1 and 3, as they cannot be taken simultaneously. I noticed a significant improvement in my joints' condition within a month of use. My knees have especially benefited from this collagen.
Read More
7.5
Relieved back pain
I truly believe this product is aiding my degenerative disc disease. For the past few months, I've suffered from debilitating pain in my lower back. After discovering my mild degenerative disc disease through x-rays, I wanted to heal from within before starting physical therapy. Given that collagen production declines with age, I chose this supplement for its joint benefits. After a few weeks of consistent use, I already feel better and stronger. It's a great value, unlike many collagen products that only focus on types I & III.
Read More
7.5
Effective preventive agent
This is a fantastic collagen for joints! Specifically type 2, it acts as a preventive agent against rheumatism, arthritis, and various inflammatory diseases.
Read More
7.5
Overall effectiveness noted
Regularly purchase a large package for my relatives aged 50 and over. They take it consistently to combat joint disease and for preventive purposes. Based on numerous reviews, noticeable improvements have been reported, and they've been using it for several years. It truly works! 👍🏻
Read More
Frequently Asked Questions
9
Obvious joint improvement
2 people found this helpful
GREAT FOR JOINTS! Type 2 collagen is particularly beneficial for combating joint and cartilage diseases. The product also contains Chondroitin sulfate and Hyaluronic acid. It's crucial to select either type 2 collagen or types 1 and 3, as they cannot be taken simultaneously. I noticed a significant improvement in my joints' condition within a month of use. My knees have especially benefited from this collagen.
7.5
Relieved back pain
I truly believe this product is aiding my degenerative disc disease. For the past few months, I've suffered from debilitating pain in my lower back. After discovering my mild degenerative disc disease through x-rays, I wanted to heal from within before starting physical therapy. Given that collagen production declines with age, I chose this supplement for its joint benefits. After a few weeks of consistent use, I already feel better and stronger. It's a great value, unlike many collagen products that only focus on types I & III.
7.5
Overall effectiveness noted
Regularly purchase a large package for my relatives aged 50 and over. They take it consistently to combat joint disease and for preventive purposes. Based on numerous reviews, noticeable improvements have been reported, and they've been using it for several years. It truly works! 👍🏻
8
Collagen source shows varying effectiveness
We explored the beneficial effects of collagen hydrolysate derived from salmon skin on atherosclerosis, a key contributor to cardiovascular diseases. The study showed that this collagen extract exhibits promising anti-inflammatory and antioxidant properties.
In tests with mice, it effectively reduced arterial thickening and plaque formation without side effects, comparable to the effects of aspirin. However, the results indicate that while collagen from salmon skin has potential, more research is needed before making definitive claims.
In tests with mice, it effectively reduced arterial thickening and plaque formation without side effects, comparable to the effects of aspirin. However, the results indicate that while collagen from salmon skin has potential, more research is needed before making definitive claims.
8
Collagen supplements may reduce cardiovascular risks
We explored the impact of collagen peptide supplementation (CPS) on cardiovascular disease markers through a careful review of randomized, placebo-controlled trials. Our analysis of twelve studies found that CPS had promising effects, including a decrease in harmful LDL cholesterol and systolic blood pressure, as well as reductions in fat mass.
However, we're clear that CPS did not show any significant effects on blood sugar levels. While these findings are encouraging, further research on CPS with longer durations is needed to fully understand its potential benefits for cardiovascular health.
However, we're clear that CPS did not show any significant effects on blood sugar levels. While these findings are encouraging, further research on CPS with longer durations is needed to fully understand its potential benefits for cardiovascular health.
9
We examined the potential of collagen-derived peptides from salmon to combat heart disease, specifically atherosclerosis, in a study involving ApoE mice.
Our findings showed that the peptide OGEFG (OG-5) effectively reduced platelet aggregation and thrombosis by targeting specific receptors and signaling pathways. Additionally, it demonstrated anti-inflammatory effects and decreased atherosclerotic plaque formation compared to traditional treatments like aspirin.
Overall, collagen hydrolysates appear to be a promising dietary supplement for heart health.
Our findings showed that the peptide OGEFG (OG-5) effectively reduced platelet aggregation and thrombosis by targeting specific receptors and signaling pathways. Additionally, it demonstrated anti-inflammatory effects and decreased atherosclerotic plaque formation compared to traditional treatments like aspirin.
Overall, collagen hydrolysates appear to be a promising dietary supplement for heart health.
8
We explored the potential of collagen hydrolysates from fish skin to impact cardiovascular health, particularly their antiplatelet activity. Eleven peptides were isolated, and nine displayed a Pro-Gly or Hyp-Gly sequence that effectively inhibited platelet aggregation in lab tests. Among these, OGSA showed the strongest effects without increasing bleeding risks. With molecular docking studies suggesting interactions with specific receptors, these peptides may hold promise as dietary supplements for cardiovascular disease prevention.
References
- Liu H, Yang Y, Liu Y, Cui L, Fu L, et al. Various bioactive peptides in collagen hydrolysate from salmo salar skin and the combined inhibitory effects on atherosclerosis in vitro and in vivo. Food Res Int. 2022;157:111281. doi:10.1016/j.foodres.2022.111281
- Jalili Z, Jalili F, Moradi S, Bagheri R, Moosavian SP, et al. Effects of collagen peptide supplementation on cardiovascular markers: a systematic review and meta-analysis of randomised, placebo-controlled trials. Br J Nutr. 2023;129:779. doi:10.1017/S0007114522001301
- Yang Y, Liu H, Cui L, Liu Y, Fu L, et al. A Collagen-Derived Oligopeptide from Salmo salar Collagen Hydrolysates Restrains Atherogenesis in ApoE Mice via Targeting P Y Receptor. Mol Nutr Food Res. 2022;66:e2200166. doi:10.1002/mnfr.202200166
- Tian Q, Li SM, Li B. The Pro-Gly or Hyp-Gly Containing Peptides from Absorbates of Fish Skin Collagen Hydrolysates Inhibit Platelet Aggregation and Target PY Receptor by Molecular Docking. Foods. 2021;10. doi:10.3390/foods10071553
- Sugita C, Yamashita A, Tsutsumi S, Kai H, Sonoda T, et al. Brazilian propolis (AF-08) inhibits collagen-induced platelet aggregation without affecting blood coagulation. J Nat Med. 2021;75:975. doi:10.1007/s11418-021-01518-w
